THE PROGRAM

The Training Program in Integrative Membrane Biology is designed to train doctoral students in the physiology, biophysics, biochemistry, structure, and cell and molecular biology of biological membranes. The central idea motivating the program is that biological membranes, and especially plasma membranes, are the arbiters and integrators of a cell's response to its environment.  Trainees select from a menu of basic courses in biochemistry, molecular and cell biology, physiology and neuroscience, and, in addition take specialized courses in membrane biochemistry and biophysics. These foundation courses place special emphasis on the structure and function of membrane macromolecules and the ways in which they control membrane permeability and cellular function.

The students in their second year may choose among courses on molecular biology and neuropharmacology, imaging methods in membrane biology, hormone-receptor interactions, the role of membranes in synaptic transmission, cell-cell recognition, the control of muscle contraction, and the cell and developmental biology of muscle and nerve.  Regular journal clubs are also held on these and related topics.  In addition, "Readings" and "Special Topics" courses can be organized by individual students and faculty members. Students meet regularly to discuss coursework and research, and to formulate suggestions regarding the program. Several courses have been started at the suggestion of students.

Advancement to candidacy for the Ph.D. follows successful performance in departmental qualifying examinations, usually taken at the end of the second year of study. Students are encouraged to begin their thesis research in their second year of study, following laboratory rotations designed to introduce a variety of techniques and approaches used for the study of biological membranes. Students are free to pursue their doctoral research with any faculty member within the Membrane Biology Training Program, regardless of departmental affiliation.

The program is an interdepartmental program but does not grant a degree. Instead, students receive degrees in the departments or programs in which they are enrolled. The Membrane program encourages participation by students in all departments and degree granting-programs in the School of Medicine.