FACULTY Thomas W. Abrams, Ph.D. University of Washington (1981); Associate Professor of Pharmacology & Experimental Therapeutics. Understanding the cellular and molecular mechanisms that underlie synaptic changes during learning. Edson X. Albuquerque, M.D., Ph.D. University of Recife, Brazil (1962); Professor and Chairman of Pharmacology & Experimental Therapeutics. Neuropharmacology of excitable membranes. Bradley E. Alger, Ph.D. Harvard University (1977); Professor of Physiology. Electrophysiological analysis of excitability in hippocampal neurons. Toni M. Antalis, Ph.D. Rice University (1981); Professor of Physiology. Molecular and cell biology of cancer and angiogenesis with an emphasis on the roles of proteases in the regulation of transcription factors, cell signaling and extracellular matrix remodeling. Laure Aurelian, Ph.D. Johns Hopkins University (1966); Professor of Pharmacology & Experimental Therapeutics. Molecular biology of herpes simplex virus pathogenesis: signaling, oncogenesis and apoptosis. Thomas Blanpied, Ph.D. University of Pittsburgh (1995); Assistant Professor of Physiology. Protein trafficking mechanisms underlying synaptic function and synapse plasticity. Mordecai P. Blaustein, M.D. Washington University (1962); Professor of Physiology. Calcium: metabolism in presynaptic nerve terminals, role in transmitter release, transport in nerve and muscle. Robert J. Bloch, Ph.D. Harvard University (1972); Professor of Physiology. ACh receptor, membrane organization and the membrane skeleton, synaptogenesis. Meredith Bond, Ph.D. University of Pennsylvania (1984); Professor and Chair of Physiology. b-adrenergic pathways in heart disease, regulation of phosphorylation of myofibrillar proteins; role of A-kinase anchoring proteins; genomic and proteomic analysis of human heart failure. Gary Fiskum, Ph.D. St. Louis University (1978); Professor of Anesthesiology. Intracellular calcium, free radical-dependent alterations to macromolecules, mitochondrial dysfunction and altered cerebral energy metabolism in ischemic brain injury. Donald L. Gill, Ph.D. University of London (1978); Professor of Biochemistry & Molecular Biology. Calcium signaling mechanisms in cells. Lawrence Goldman, Ph.D. University of California, Los Angeles (1964); Professor of Physiology. Membrane biophysics, electrical signal generation by cell membranes. John M. Hamlyn, Ph.D. College of Technology, Glasgow, Scotland (1979); Professor of Physiology. Mechanisms of hypertension. Joseph P.Y. Kao, Ph.D. University of California, Berkeley (1985); Associate Professor of Physiology. Development of fluorescent and photochemical probes of cell activation. Bruce K. Krueger, Ph.D. Yale University (1975); Professor of Physiology. Cellular and molecular mechanisms of neuronal survival. H. Moo Kwon, Ph.D. SUNY Buffalo (1987); Professor of Physiology. Osmotic regulation of transcription in the kidney. Joseph R. Lakowicz, Ph.D. University of Illinois (1973); Professor of Biochemistry & Molecular Biology. Fluorescence spectroscopy of macromolecules and membranes. W. Jonathan Lederer, M.D., Ph.D. Yale University (1975); Professor of Physiology. Cellular mechanisms regulating excitation and contraction in heart muscle. David Litwack, Ph.D. M.I.T. (1995); Assistant Professor of Anatomy & Neurobiology. Molecular activities and axon guidance molecules that regulate the formation of topography in the developing corticopontine system. Stuart Martin, Ph.D. University of California-San Diego (1998); Assistant Professor of Physiology. Breast tumor metastasis; apoptotic cell death; cytoskeleton and cell motility. Margaret M. McCarthy, Ph.D. Rutgers University (1989); Professor of Physiology and Psychiatry and Assistant Dean for Graduate Studies. GABA and glutamate receptors and Ca signaling in cortical development. Andrea Meredith, Ph.D. University of Texas (2000); Assistant Professor of Physiology. Mervyn Monteiro, Ph.D. MRC National Inst. for Medical Res, England (1983); Professor of Medical Biotechnology Center & Neurology. Molecular genetics of proteins involved in neurodegenerative diseases. Steven D. Munger, Ph.D. University of Florida (1997); Associate Professor of Anatomy and Neurobiology. Molecular basis of odor and taste transduction; structure/function of odor and taste receptors; genetics of taste, eating and disease. James P. Nataro, M.D., Ph.D. University of Maryland School of Medicine (1987); Professor of Pediatrics. Interactions of bacterial toxins with the membrane skeleton. Elizabeth Powell, Ph.D. Rutgers University (1997); Assistant Professor of Anatomy and Neurobiology. Forebrain development and the roles of inhibitory neurons in cognition and behavior, particularly epilepsy and autism. Yun Qiu, Ph.D. Rutgers University (1995); Associate Professor of Pharmacology & Experimental Therapeutics. Signal transduction by protein kinases, mechanisms of drug resistance and tumor metastasis, mouse models of prostate cancer. William R. Randall, Ph.D. University of California, Davis (1983); Associate Professor of Pharmacology & Experimental Therapeutics. Molecular neurobiology of acetylcholinesterase and acetylcholine receptors. Mark Rizzo, Ph.D. University of Pittsburgh (2000); Assistant Professor of Physiology. Regulation of insulin secretion by polypeptide hormones; receptor tryosine kinase signal transduction. Terry Rogers, Ph.D. University of California, Davis (1977); Professor of Biochemistry & Molecular Biology. Membrane receptors for toxins, drugs and hormones in myocardial and neuronal cells. Martin F. Schneider, Ph.D. Duke University (1969); Professor of Biochemistry & Molecular Biology. Calcium regulation in skeletal muscle and other cells. Scott Thompson, Ph.D. Stanford University (1986); Professor of Physiology. Synaptic transmission and plasticity in the CNS, under normal and pathological conditions. Matthew C. Trudeau, Ph.D. University of Wisconsin-Madison (1998); Assistant Professor of Physiology. Molecular mechanisms in ion channels; specific interest in 'HERG', a voltage-activated potassium channel from heart and its role in familial and acquired cardiac syndromes. James B. Wade, Ph.D. Princeton University (1972); Professor of Physiology. Structure function relationships in epithelia. David J. Weber, Ph.D. University of North Carolina (1988); Professor of Biochemistry & Molecular Biology. Regulation of the Ryanodine receptor via interactions with the calcium-binding proteins S100A1 and CaM. Daniel Weinreich, Ph.D. University of Utah (1970); Professor of Pharmacology & Experimental Therapeutics. Immunoregulation of neuronal excitability. Paul A. Welling, M.D. University of Kansas (1988); Professor of Physiology. Molecular physiology of ion channels in epithelia; molecular basis of actions of mineralocorticoid hormone action. W. Gil Wier, Ph.D. University of Utah (1978); Professor of Physiology. Role of intracellular Ca in excitation- contraction coupling in heart muscle. Li Zhang, Ph.D. University of Notre Dame (1991); Associate Professor of Physiology. |